Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor

Particulate Guanylyl Cyclase Receptor A (pGC-A) is a natriuretic peptide membrane receptor, playing a vital role in controlling cardiovascular, renal, and endocrine functions. The extracellular domain interacts with natriuretic peptides and triggers the intracellular guanylyl cyclase domain to conve...

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Detalles Bibliográficos
Autores principales: Zhang, Shangji, Hansen, Debra T., Martin-Garcia, Jose M., Zook, James D., Pan, Shuchong, Craciunescu, Felicia M., Burnett, John C., Fromme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276669/
https://www.ncbi.nlm.nih.gov/pubmed/35821229
http://dx.doi.org/10.1038/s41598-022-15798-z

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