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TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1

CVB3 is a single positive-strand enterovirus, and a common pathogen in myocarditis etiology. Although a number of antiviral candidates are under development, specific targeted therapy is not available for CVB3. Ferroptosis is a new type of regulatory cell death discovered in recent years. In this st...

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Detalles Bibliográficos
Autores principales: Yi, Lu, Hu, Yanan, Wu, Zhixiang, Li, Ying, Kong, Min, Kang, Zhijuan, Zuoyuan, Bojiao, Yang, Zuocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276735/
https://www.ncbi.nlm.nih.gov/pubmed/35821227
http://dx.doi.org/10.1038/s41419-022-05027-w