Cargando…

Intratracheal administration of mesenchymal stem cells modulates lung macrophage polarization and exerts anti-asthmatic effects

Mesenchymal stem cells (MSCs) possess immunomodulatory properties that have therapeutic potential for the treatment of inflammatory diseases. This study investigates the effects of direct MSC administration on asthmatic airways. Umbilical cord MSCs (ucMSCs) were intratracheally administered to six-w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mo, Yosep, Kang, Hanbit, Bang, Ji-Young, Shin, Jae Woo, Kim, Hye Young, Cho, Sang-Heon, Kang, Hye-Ryun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276742/ https://www.ncbi.nlm.nih.gov/pubmed/35821386 http://dx.doi.org/10.1038/s41598-022-14846-y

Ejemplares similares

Intravenous Mesenchymal Stem Cell Administration Modulates Monocytes/Macrophages and Ameliorates Asthmatic Airway Inflammation in a Murine Asthma Model
por: Mo, Yosep, et al.
Publicado: (2022)

Mesenchymal stem cells exert their anti-asthmatic effects through macrophage modulation in a murine chronic asthma model
por: Kim, Ruth Lee, et al.
Publicado: (2022)

Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous administration in a mouse model of pulmonary fibrosis
por: Choi, Sun Mi, et al.
Publicado: (2023)

Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model
por: Mo, Yosep, et al.
Publicado: (2022)

CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics
por: Yim, Eun-Young, et al.
Publicado: (2013)

Tranglutaminase 2 contributes to the asthmatic inflammation by modulating activation of alveolar macrophages
por: Lee, Hyun Seung, et al.
Publicado: (2021)

Thalidomide Inhibits Alternative Activation of Macrophages In Vivo and In Vitro: A Potential Mechanism of Anti-Asthmatic Effect of Thalidomide
por: Lee, Hyun Seung, et al.
Publicado: (2015)

Lost to Follow-Up in Asthmatics Does Not Mean Treatment Failure: Causes and Clinical Outcomes of Non-Adherence To Outpatient Treatment In Adult Asthma
por: Kang, Min-Gyu, et al.
Publicado: (2013)

Reduced IRF7 response to rhinovirus unrelated with DNA methylation in peripheral mononuclear cells of adult asthmatics
por: Kim, Sae-Hoon, et al.
Publicado: (2015)

Clinical characteristics and long-term outcomes related to sputum eosinophilia in Korean asthmatics
por: Jung, Jae-Woo, et al.
Publicado: (2011)

An Apparatus for the Intratracheal Administration of Ether
por: Shipway, F. E.
Publicado: (1913)

Airway Smooth Muscle Sensitivity to Methacholine in Precision-Cut Lung Slices (PCLS) from Ovalbumin-induced Asthmatic Mice
por: Kim, Hae Jin, et al.
Publicado: (2015)

Oral, subcutaneous and intratracheal administration of carcinogenic lactones and related substances: the intratracheal administration of cigarette tar in the rat.
por: Dickens, F., et al.
Publicado: (1966)

THE EFFECTS OF THE INTRATRACHEAL ADMINISTRATION OF FOREIGN SERUM
por: Jones, F. S.
Publicado: (1924)

THE EXPERIMENTAL PRODUCTION IN DOGS OF EMPHYSEMA WITH ASSOCIATED ASTHMATIC SYNDROME BY MEANS OF AN INTRATRACHEAL BALL VALVE
por: Harris, Willam H., et al.
Publicado: (1919)

Multifaceted interventions to reduce acute exacerbations in elderly asthmatics
por: Lee, So-Hee, et al.
Publicado: (2018)

Memory Function, Neurological, and Immunological Biomarkers in Allergic Asthmatic Mice Intratracheally Exposed to Bisphenol A
por: Win-Shwe, Tin-Tin, et al.
Publicado: (2019)

Targeting murine alveolar macrophages by the intratracheal administration of locked nucleic acid containing antisense oligonucleotides
por: Uemura, Yasunori, et al.
Publicado: (2019)

Altered T cell and monocyte subsets in prolonged immune reconstitution inflammatory syndrome related with DRESS (drug reaction with eosinophilia and systemic symptoms)
por: Kang, Sung-Yoon, et al.
Publicado: (2020)

Intratracheal administration of adipose derived mesenchymal stem cells alleviates chronic asthma in a mouse model
por: Dai, Ranran, et al.
Publicado: (2018)

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype
por: Chung, Sangwoon, et al.
Publicado: (2016)

The impact of sinusitis on the long-term clinical outcomes of asthma
por: Kim, Min-Hye, et al.
Publicado: (2014)

Intratracheal Injections
Publicado: (1891)

Intratracheal Insufflation
por: Ricketts, Benjamin Merrill
Publicado: (1916)

Intratracheal Medication
por: Forsyth, Edgar A.
Publicado: (1902)

Intratracheal Administration of Umbilical Cord Blood-Derived Mesenchymal Stem Cells in a Patient with Acute Respiratory Distress Syndrome
por: Chang, Youjin, et al.
Publicado: (2014)

Mesenchymal Stem Cells Suppress Severe Asthma by Directly Regulating Th2 Cells and Type 2 Innate Lymphoid Cells
por: Shin, Jae Woo, et al.
Publicado: (2021)

Intratracheal Administration of Chloroquine-Loaded Niosomes Minimize Systemic Drug Exposure
por: Saafan, Hesham A., et al.
Publicado: (2021)

The efficacy of intratracheal administration of surfactant and budesonide combination in the prevention of bronchopulmonary dysplasia
por: Gharehbaghi, Manizheh Mostafa, et al.
Publicado: (2021)

A polymorphism in the histone deacetylase 1 gene is associated with the response to corticosteroids in asthmatics
por: Kim, Min-Hye, et al.
Publicado: (2013)

Past, present, and future of pharmacovigilance in Korea
por: Kang, Dong Yoon, et al.
Publicado: (2017)

Effect of Allergic Rhinitis on the Use and Cost of Health Services by Children with Asthma
por: Kang, Hye-Young, et al.
Publicado: (2008)

Intratracheal instillation versus intratracheal inhalation: influence of cytokines on inflammatory response.
por: Osier, M, et al.
Publicado: (1997)

Direct costs of severe cutaneous adverse reactions in a tertiary hospital in Korea
por: Yang, Min-Suk, et al.
Publicado: (2019)

Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model
por: Urbanek, Konrad, et al.
Publicado: (2016)

Blockade of Airway Inflammation by Kaempferol via Disturbing Tyk-STAT Signaling in Airway Epithelial Cells and in Asthmatic Mice
por: Gong, Ju-Hyun, et al.
Publicado: (2013)

The Intratracheal Insufflation of Ether
por: Thomson, H. Torrance, et al.
Publicado: (1914)

Exuberant Intratracheal Granuloma
por: Stuart, Emelia, et al.
Publicado: (2021)

Intratracheal Administration of Endotoxin Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats
por: Shim, Jae Won, et al.
Publicado: (2008)

Intratracheal Ovalbumin Administration Induces Colitis Through the IFN-γ Pathway in Mice
por: Jung, Kyoung-Hwa, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_df0mpif3saiq295rdm0k5i72ts