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Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma

INTRODUCTION: Spinal osteoblastomas are primary benign bone tumors most commonly presenting as diffuse back pain in young adults. Rarely, spinal osteoblastoma is associated with ossification of the ligamentum flavum (OLF), a form of ectopic bone formation, which can present with myelopathy. This rep...

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Autores principales: Montgomery, Canada T., Miranda, Stephen P., Nelson, Ernest, Louka, Katie, Nasrallah, MacLean, Zhang, Paul J., Stein, Joel, Petrov, Dmitriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276984/
https://www.ncbi.nlm.nih.gov/pubmed/35846967
http://dx.doi.org/10.3389/fsurg.2022.890965
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author Montgomery, Canada T.
Miranda, Stephen P.
Nelson, Ernest
Louka, Katie
Nasrallah, MacLean
Zhang, Paul J.
Stein, Joel
Petrov, Dmitriy
author_facet Montgomery, Canada T.
Miranda, Stephen P.
Nelson, Ernest
Louka, Katie
Nasrallah, MacLean
Zhang, Paul J.
Stein, Joel
Petrov, Dmitriy
author_sort Montgomery, Canada T.
collection PubMed
description INTRODUCTION: Spinal osteoblastomas are primary benign bone tumors most commonly presenting as diffuse back pain in young adults. Rarely, spinal osteoblastoma is associated with ossification of the ligamentum flavum (OLF), a form of ectopic bone formation, which can present with myelopathy. This report highlights a unique case of a patient with spinal osteoblastoma, associated OLF, and thoracic myelopathy. CASE DESCRIPTION: The patient presented with subtle myelopathy consisting of mid-thoracic back pain, paresthesias, and gait instability. Imaging findings were suggestive of spinal osteoblastoma with multifocal OLF. The patient was consented for thoracic decompression and stabilization at the T6-10 levels. Histopathology confirmed osteoblastoma with associated OLF. At follow up, the patient’s neurological symptoms had completely resolved. CONCLUSION: This case describes management for a rare presentation of osteoblastoma with associated OLF and myelopathy. Surgeons should be wary of disproportionate neurological compromise when spinal osteoblastoma is associated with OLF. Further study is required to elucidate the pathogenesis of this condition.
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spelling pubmed-92769842022-07-14 Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma Montgomery, Canada T. Miranda, Stephen P. Nelson, Ernest Louka, Katie Nasrallah, MacLean Zhang, Paul J. Stein, Joel Petrov, Dmitriy Front Surg Surgery INTRODUCTION: Spinal osteoblastomas are primary benign bone tumors most commonly presenting as diffuse back pain in young adults. Rarely, spinal osteoblastoma is associated with ossification of the ligamentum flavum (OLF), a form of ectopic bone formation, which can present with myelopathy. This report highlights a unique case of a patient with spinal osteoblastoma, associated OLF, and thoracic myelopathy. CASE DESCRIPTION: The patient presented with subtle myelopathy consisting of mid-thoracic back pain, paresthesias, and gait instability. Imaging findings were suggestive of spinal osteoblastoma with multifocal OLF. The patient was consented for thoracic decompression and stabilization at the T6-10 levels. Histopathology confirmed osteoblastoma with associated OLF. At follow up, the patient’s neurological symptoms had completely resolved. CONCLUSION: This case describes management for a rare presentation of osteoblastoma with associated OLF and myelopathy. Surgeons should be wary of disproportionate neurological compromise when spinal osteoblastoma is associated with OLF. Further study is required to elucidate the pathogenesis of this condition. Frontiers Media S.A. 2022-06-29 /pmc/articles/PMC9276984/ /pubmed/35846967 http://dx.doi.org/10.3389/fsurg.2022.890965 Text en Copyright © 2022 Montgomery, Miranda, Nelson, Louka, Nasrallah, Zhang, Stein and Petrov. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Montgomery, Canada T.
Miranda, Stephen P.
Nelson, Ernest
Louka, Katie
Nasrallah, MacLean
Zhang, Paul J.
Stein, Joel
Petrov, Dmitriy
Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_full Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_fullStr Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_full_unstemmed Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_short Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_sort case report: multilevel ossification of the ligamentum flavum in a patient with spinal osteoblastoma
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276984/
https://www.ncbi.nlm.nih.gov/pubmed/35846967
http://dx.doi.org/10.3389/fsurg.2022.890965
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