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Candida albicans Sap6 Initiates Oral Mucosal Inflammation via the Protease Activated Receptor PAR2

Candida albicans Sap6, a secreted aspartyl protease (Sap), contributes to fungal virulence in oral candidiasis. Beside its protease activity, Sap6 contains RGD (RGDRGD) motif required for its binding to host integrins. Sap6 activates immune cells to induce proinflammatory cytokines, although its abi...

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Detalles Bibliográficos
Autores principales:	Kumar, Rohitashw, Rojas, Isolde Gina, Edgerton, Mira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277060/ https://www.ncbi.nlm.nih.gov/pubmed/35844627 http://dx.doi.org/10.3389/fimmu.2022.912748

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