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IL‐27 improves adoptive CD8(+) T cells’ antitumor activity via enhancing cell survival and memory T cell differentiation
IL‐27 is an anti‐inflammatory cytokine that triggers enhanced antitumor immunity, particularly cytotoxic T lymphocyte responses. In the present study, we sought to develop IL‐27 into a therapeutic adjutant for adoptive T cell therapy using our well‐established models. We have found that IL‐27 direct...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277268/ https://www.ncbi.nlm.nih.gov/pubmed/35441753 http://dx.doi.org/10.1111/cas.15374 |