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IL‐27 improves adoptive CD8(+) T cells’ antitumor activity via enhancing cell survival and memory T cell differentiation

IL‐27 is an anti‐inflammatory cytokine that triggers enhanced antitumor immunity, particularly cytotoxic T lymphocyte responses. In the present study, we sought to develop IL‐27 into a therapeutic adjutant for adoptive T cell therapy using our well‐established models. We have found that IL‐27 direct...

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Detalles Bibliográficos
Autores principales: Ding, Miao, Fei, Yi, Zhu, Jianmin, Ma, Ji, Zhu, Guoqing, Zhen, Ni, Zhu, Jiabei, Mao, Siwei, Sun, Fenyong, Wang, Feng, Pan, Qiuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277268/
https://www.ncbi.nlm.nih.gov/pubmed/35441753
http://dx.doi.org/10.1111/cas.15374