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Quantitative Analysis of the Protein Methylome Reveals PARP1 Methylation is involved in DNA Damage Response

Protein methylation plays important roles in DNA damage response. To date, proteome-wide profiling of protein methylation upon DNA damage has been not reported yet. In this study, using HILIC affinity enrichment combined with MS analysis, we conducted a quantitative analysis of the methylated protei...

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Detalles Bibliográficos
Autores principales: Wang, Xinzhu, Mi, Shaojie, Zhao, Mingxin, Lu, Chen, Jia, Chenxi, Chen, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277342/
https://www.ncbi.nlm.nih.gov/pubmed/35847980
http://dx.doi.org/10.3389/fmolb.2022.878646