Cargando…

Quantitative Analysis of the Protein Methylome Reveals PARP1 Methylation is involved in DNA Damage Response

Protein methylation plays important roles in DNA damage response. To date, proteome-wide profiling of protein methylation upon DNA damage has been not reported yet. In this study, using HILIC affinity enrichment combined with MS analysis, we conducted a quantitative analysis of the methylated protei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xinzhu, Mi, Shaojie, Zhao, Mingxin, Lu, Chen, Jia, Chenxi, Chen, Yali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277342/ https://www.ncbi.nlm.nih.gov/pubmed/35847980 http://dx.doi.org/10.3389/fmolb.2022.878646

Ejemplares similares

Molecular Mechanism of Selective Binding of NMS-P118 to PARP-1 and PARP-2: A Computational Perspective
por: Wang, Ran, et al.
Publicado: (2020)

Activation of a Mitogen-Activated Protein Kinase Hog1 by DNA Damaging Agent Methyl Methanesulfonate in Yeast
por: Huang, Shan, et al.
Publicado: (2020)

The potential of PARP inhibitors in targeted cancer therapy and immunotherapy
por: Hunia, Jaromir, et al.
Publicado: (2022)

Quantitative Proteomics Analysis of FFPE Tumor Samples Reveals the Influences of NET-1 siRNA Nanoparticles and Sonodynamic Therapy on Tetraspanin Protein Involved in HCC
por: Wu, Bolin, et al.
Publicado: (2021)

Immunological Significance of Prognostic DNA Methylation Sites in Hepatocellular Carcinoma
por: Xu, Qianhui, et al.
Publicado: (2021)

A DNA Methylation-Based Panel for the Prognosis and Diagnosis of Patients With Breast Cancer and Its Mechanisms
por: Liu, Xiao-Ping, et al.
Publicado: (2020)

Mechanisms for Maintaining Eukaryotic Replisome Progression in the Presence of DNA Damage
por: Guilliam, Thomas A.
Publicado: (2021)

Searching for DNA Damage: Insights From Single Molecule Analysis
por: Schaich, Matthew A., et al.
Publicado: (2021)

Methylation of cell-free circulating DNA in the diagnosis of cancer
por: Warton, Kristina, et al.
Publicado: (2015)

Fumarase: From the TCA Cycle to DNA Damage Response and Tumor Suppression
por: Leshets, Michael, et al.
Publicado: (2018)

Nucleosome Remodeling by Fun30(SMARCAD1) in the DNA Damage Response
por: Bantele, Susanne C. S., et al.
Publicado: (2019)

Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations With Phenotype
por: Quan, Yuan, et al.
Publicado: (2021)

Network-Based Expression Analyses and Experimental Verifications Reveal the Involvement of STUB1 in Acute Kidney Injury
por: Shi, Yanting, et al.
Publicado: (2021)

Beyond the Trinity of ATM, ATR, and DNA-PK: Multiple Kinases Shape the DNA Damage Response in Concert With RNA Metabolism
por: Burger, Kaspar, et al.
Publicado: (2019)

Requirements for MRN endonuclease processing of topoisomerase II-mediated DNA damage in mammalian cells
por: Sun, Yilun, et al.
Publicado: (2022)

Tumor-Related Methylated Cell-Free DNA and Circulating Tumor Cells in Melanoma
por: Salvianti, Francesca, et al.
Publicado: (2016)

The emerging field of opportunities for single-cell DNA methylation studies in hematology and beyond
por: Albinati, Leone, et al.
Publicado: (2023)

ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance
por: Drápela, Stanislav, et al.
Publicado: (2020)

MiR-4521 perturbs FOXM1-mediated DNA damage response in breast cancer
por: Kuthethur, Raviprasad, et al.
Publicado: (2023)

Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation
por: Yang, Zhen, et al.
Publicado: (2022)

DNA Damage Response Gene-Based Subtypes Associated With Clinical Outcomes in Early-Stage Lung Adenocarcinoma
por: Zhao, Yang, et al.
Publicado: (2022)

Conformational Dynamics of DNA Polymerases Revealed at the Single-Molecule Level
por: Millar, David P.
Publicado: (2022)

Integrated Metabolomics-DNA Methylation Analysis Reveals Significant Long-Term Tissue-Dependent Directional Alterations in Aminoacyl-tRNA Biosynthesis in the Left Ventricle of the Heart and Hippocampus Following Proton Irradiation
por: Torres, Eileen Ruth S., et al.
Publicado: (2019)

DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner
por: Song, Yawei, et al.
Publicado: (2020)

Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy
por: Harrision, Daniel, et al.
Publicado: (2020)

Erratum: A DNA Methylation-Based Panel for the Prognosis and Diagnosis of Patients With Breast Cancer and Its Mechanisms
por: Frontiers Production Office,
Publicado: (2020)

Aberrant DNA Methylation-Mediated FOXF2 Dysregulation Is a Prognostic Risk Factor for Gastric Cancer
por: Zhang, Cheng, et al.
Publicado: (2021)

Platelet Mitochondrial DNA Methylation as Epigenetic Biomarker of Short-Term Air Pollution Exposure in Healthy Subjects
por: Sun, Huimin, et al.
Publicado: (2022)

DNA Damage in Healthy Individuals and Respiratory Patients after Treating Whole Blood In vitro with the Bulk and Nano Forms of NSAIDs
por: Najafzadeh, Mojgan, et al.
Publicado: (2016)

Integrative Predictive Modeling of Metastasis in Melanoma Cancer Based on MicroRNA, mRNA, and DNA Methylation Data
por: Kutlay, Ayşegül, et al.
Publicado: (2021)

Identification of Tumor Microenvironment and DNA Methylation-Related Prognostic Signature for Predicting Clinical Outcomes and Therapeutic Responses in Cervical Cancer
por: Liu, Bangquan, et al.
Publicado: (2022)

In vivo Proximity Labeling of Nuclear and Nucleolar Proteins by a Stably Expressed, DNA Damage-Responsive NONO-APEX2 Fusion Protein
por: Trifault, Barbara, et al.
Publicado: (2022)

Quantitative Proteomic Analysis in Alveolar Type II Cells Reveals the Different Capacities of RAS and TGF-β to Induce Epithelial–Mesenchymal Transition
por: Zhou, Yilu, et al.
Publicado: (2021)

Computational Study on DNA Repair: The Roles of Electrostatic Interactions Between Uracil-DNA Glycosylase (UDG) and DNA
por: Xie, Yixin, et al.
Publicado: (2021)

Quantitative Cryo-Electron Tomography
por: Navarro, Paula P.
Publicado: (2022)

Editorial: Using multi-omics to develop new strategies to improve prognosis and immunotherapy outcomes in cancers
por: Cao, Chenxi, et al.
Publicado: (2023)

Mammalian Resilience Revealed by a Comparison of Human Diseases and Mouse Models Associated With DNA Helicase Deficiencies
por: Kohzaki, Masaoki
Publicado: (2022)

Editorial: Drug Delivery System Based on Nanoparticles for Inflammation and Cancer Therapy
por: Zhang, Mingxin, et al.
Publicado: (2022)

Genome-wide Characterization of the JmjC Domain-Containing Histone Demethylase Gene Family Reveals GhJMJ24 and GhJMJ49 Involving in Somatic Embryogenesis Process in Cotton
por: Li, Yan, et al.
Publicado: (2022)

N-3 Polyunsaturated Fatty Acid Dehydrogenase Fat-1 Regulates Mitochondrial Energy Metabolism by Altering DNA Methylation in Isolated Cells of Transgenic Cattle
por: Wang, Xueqiao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h1tmh0nqdq44g608lgu57ga2fu