Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide–chlorambucil conjugate

Renal cell carcinoma with Xp11.2 translocation involving the TFE3 gene (TFE3‐RCC) is a recently identified subset of RCC with unique morphology and clinical presentation. The chimeric PRCC‐TFE3 protein produced by Xp11.2 translocation has been shown to transcriptionally activate its downstream targe...

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Detalles Bibliográficos
Autores principales: Funasaki, Shintaro, Mehanna, Sally, Ma, Wenjuan, Nishizawa, Hidekazu, Kamikubo, Yasuhiko, Sugiyama, Hiroshi, Ikeda, Shuji, Motoshima, Takanobu, Hasumi, Hisashi, Linehan, W. Marston, Schmidt, Laura S., Ricketts, Chris, Suda, Toshio, Oike, Yuichi, Kamba, Tomomi, Baba, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277412/
https://www.ncbi.nlm.nih.gov/pubmed/35396773
http://dx.doi.org/10.1111/cas.15364

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