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COVID-19 and the hidden threat of diabetic microvascular complications

The coronavirus disease 2019 (COVID-19) pandemic affected at least 200 million individuals worldwide and resulted in nearly 5 million deaths as of October 2021. According to the latest data from the International Diabetes Federation (IDF) in 2021, the diabetes pandemic has affected 537 million peopl...

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Autores principales: Zaghloul, Hadeel, Malik, Rayaz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277425/
https://www.ncbi.nlm.nih.gov/pubmed/35847423
http://dx.doi.org/10.1177/20420188221110708
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author Zaghloul, Hadeel
Malik, Rayaz A.
author_facet Zaghloul, Hadeel
Malik, Rayaz A.
author_sort Zaghloul, Hadeel
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description The coronavirus disease 2019 (COVID-19) pandemic affected at least 200 million individuals worldwide and resulted in nearly 5 million deaths as of October 2021. According to the latest data from the International Diabetes Federation (IDF) in 2021, the diabetes pandemic has affected 537 million people and is associated with 6.7 million deaths. Given the high prevalence of both diabetes and COVID-19 and common pathological outcomes, a bidirectional relationship could have a catastrophic outcome. The increased risk of COVID-19 in those with obesity and diabetes and higher morbidity and mortality has received considerable attention. However, little attention has been given to the relationship between COVID-19 and microvascular complications. Indeed, microvascular complications are associated with an increased risk of cardiovascular disease (CVD) and mortality in diabetes. This review assesses the evidence for an association between diabetic microvascular complications (neuropathy, nephropathy, and retinopathy) and COVID-19. It draws parallels between the pathological changes occurring in the microvasculature in both diseases and assesses whether microvascular disease is a prognostic factor for COVID-19 outcomes in diabetes.
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spelling pubmed-92774252022-07-14 COVID-19 and the hidden threat of diabetic microvascular complications Zaghloul, Hadeel Malik, Rayaz A. Ther Adv Endocrinol Metab Review The coronavirus disease 2019 (COVID-19) pandemic affected at least 200 million individuals worldwide and resulted in nearly 5 million deaths as of October 2021. According to the latest data from the International Diabetes Federation (IDF) in 2021, the diabetes pandemic has affected 537 million people and is associated with 6.7 million deaths. Given the high prevalence of both diabetes and COVID-19 and common pathological outcomes, a bidirectional relationship could have a catastrophic outcome. The increased risk of COVID-19 in those with obesity and diabetes and higher morbidity and mortality has received considerable attention. However, little attention has been given to the relationship between COVID-19 and microvascular complications. Indeed, microvascular complications are associated with an increased risk of cardiovascular disease (CVD) and mortality in diabetes. This review assesses the evidence for an association between diabetic microvascular complications (neuropathy, nephropathy, and retinopathy) and COVID-19. It draws parallels between the pathological changes occurring in the microvasculature in both diseases and assesses whether microvascular disease is a prognostic factor for COVID-19 outcomes in diabetes. SAGE Publications 2022-07-11 /pmc/articles/PMC9277425/ /pubmed/35847423 http://dx.doi.org/10.1177/20420188221110708 Text en © The Author(s), 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Zaghloul, Hadeel
Malik, Rayaz A.
COVID-19 and the hidden threat of diabetic microvascular complications
title COVID-19 and the hidden threat of diabetic microvascular complications
title_full COVID-19 and the hidden threat of diabetic microvascular complications
title_fullStr COVID-19 and the hidden threat of diabetic microvascular complications
title_full_unstemmed COVID-19 and the hidden threat of diabetic microvascular complications
title_short COVID-19 and the hidden threat of diabetic microvascular complications
title_sort covid-19 and the hidden threat of diabetic microvascular complications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277425/
https://www.ncbi.nlm.nih.gov/pubmed/35847423
http://dx.doi.org/10.1177/20420188221110708
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