Differentiation of Pluripotent Stem Cells Into Thymic Epithelial Cells and Generation of Thymic Organoids: Applications for Therapeutic Strategies Against APECED

The thymus is a primary lymphoid organ essential for the induction of central immune tolerance. Maturing T cells undergo several steps of expansion and selection mediated by thymic epithelial cells (TECs). In APECED and other congenital pathologies, a deficiency in genes that regulate TEC developmen...

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Detalles Bibliográficos
Autores principales: Provin, Nathan, Giraud, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277542/
https://www.ncbi.nlm.nih.gov/pubmed/35844523
http://dx.doi.org/10.3389/fimmu.2022.930963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277542/
https://www.ncbi.nlm.nih.gov/pubmed/35844523
http://dx.doi.org/10.3389/fimmu.2022.930963

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