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Data-Driven Analyses of Longitudinal Hippocampal Imaging Trajectories: Discrimination and Biomarker Prediction of Change Classes

BACKGROUND: Hippocampal atrophy is a well-known biomarker of neurodegeneration, such as that observed in Alzheimer’s disease (AD). Although distributions of hippocampal volume trajectories for asymptomatic individuals often reveal substantial heterogeneity, it is unclear whether interpretable trajec...

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Detalles Bibliográficos
Autores principales: Drouin, Shannon M., McFall, G. Peggy, Potvin, Olivier, Bellec, Pierre, Masellis, Mario, Duchesne, Simon, Dixon, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277685/
https://www.ncbi.nlm.nih.gov/pubmed/35570482
http://dx.doi.org/10.3233/JAD-215289