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A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells

BACKGROUND: Mantle cell lymphoma (MCL) is a rare, highly heterogeneous type of B-cell non-Hodgkin’s lymphoma. The sumoylation pathway is known to be upregulated in many cancers including lymphoid malignancies. However, little is known about its oncogenic role in MCL. METHODS: Levels of sumoylation e...

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Detalles Bibliográficos
Autores principales: Hanel, Walter, Lata, Pushpa, Youssef, Youssef, Tran, Ha, Tsyba, Liudmyla, Sehgal, Lalit, Blaser, Bradley W., Huszar, Dennis, Helmig-Mason, JoBeth, Zhang, Liwen, Schrock, Morgan S., Summers, Matthew K., Chan, Wing Keung, Prouty, Alexander, Mundy-Bosse, Bethany L., Chen-Kiang, Selina, Danilov, Alexey V., Maddocks, Kami, Baiocchi, Robert A., Alinari, Lapo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277803/
https://www.ncbi.nlm.nih.gov/pubmed/35831896
http://dx.doi.org/10.1186/s40164-022-00293-y