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BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats

AIM: The aim of this study was to investigate the renoprotective effects of exosomes derived from rat bone marrow mesenchymal stem cells (rBMSCs) in a rat model of 5/6 nephrectomy (Nx)-induced chronic kidney disease (CKD). METHODS: A rat model of 5/6 Nx-induced CKD was established using conventional...

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Detalles Bibliográficos
Autores principales: Wan, Feng, Yang, Ru-chun, Tang, Yue-wen, Tang, Xuan-li, Ye, Tian, Zheng, Jie, Zhang, Hua-qin, Lin, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277829/
https://www.ncbi.nlm.nih.gov/pubmed/35820962
http://dx.doi.org/10.1186/s40001-022-00742-8

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