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BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats
AIM: The aim of this study was to investigate the renoprotective effects of exosomes derived from rat bone marrow mesenchymal stem cells (rBMSCs) in a rat model of 5/6 nephrectomy (Nx)-induced chronic kidney disease (CKD). METHODS: A rat model of 5/6 Nx-induced CKD was established using conventional...
Autores principales: | Wan, Feng, Yang, Ru-chun, Tang, Yue-wen, Tang, Xuan-li, Ye, Tian, Zheng, Jie, Zhang, Hua-qin, Lin, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277829/ https://www.ncbi.nlm.nih.gov/pubmed/35820962 http://dx.doi.org/10.1186/s40001-022-00742-8 |
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