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A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish

BACKGROUND: Telomerase, the enzyme capable of elongating telomeres, is usually restricted in human somatic cells, which contributes to progressive telomere shortening with cell-division and ageing. T and B-cells cells are somatic cells that can break this rule and can modulate telomerase expression...

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Detalles Bibliográficos
Autores principales: Ellis, Pam S., Martins, Raquel R., Thompson, Emily J., Farhat, Asma, Renshaw, Stephen A., Henriques, Catarina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277892/
https://www.ncbi.nlm.nih.gov/pubmed/35820929
http://dx.doi.org/10.1186/s12979-022-00287-8