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A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish
BACKGROUND: Telomerase, the enzyme capable of elongating telomeres, is usually restricted in human somatic cells, which contributes to progressive telomere shortening with cell-division and ageing. T and B-cells cells are somatic cells that can break this rule and can modulate telomerase expression...
Autores principales: | Ellis, Pam S., Martins, Raquel R., Thompson, Emily J., Farhat, Asma, Renshaw, Stephen A., Henriques, Catarina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277892/ https://www.ncbi.nlm.nih.gov/pubmed/35820929 http://dx.doi.org/10.1186/s12979-022-00287-8 |
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