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Chemokine CXCL12 drives pericyte accumulation and airway remodeling in allergic airway disease
BACKGROUND: Airway remodeling is a significant contributor to impaired lung function in chronic allergic airway disease. Currently, no therapy exists that is capable of targeting these structural changes and the consequent loss of function. In the context of chronic allergic inflammation, pericytes...
Autores principales: | Bignold, Rebecca, Shammout, Bushra, Rowley, Jessica E., Repici, Mariaelena, Simms, John, Johnson, Jill R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277926/ https://www.ncbi.nlm.nih.gov/pubmed/35831901 http://dx.doi.org/10.1186/s12931-022-02108-4 |
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