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Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression

BACKGROUND: The complement system is part of the innate immune system that clears pathogens and cellular debris. In the healthy brain, complement influences neurodevelopment and neurogenesis, synaptic pruning, clearance of neuronal blebs, recruitment of phagocytes, and protects from pathogens. Howev...

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Detalles Bibliográficos
Autores principales:	Carvalho, Klebea, Schartz, Nicole D., Balderrama-Gutierrez, Gabriela, Liang, Heidi Y., Chu, Shu-Hui, Selvan, Purnika, Gomez-Arboledas, Angela, Petrisko, Tiffany J., Fonseca, Maria I., Mortazavi, Ali, Tenner, Andrea J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277945/ https://www.ncbi.nlm.nih.gov/pubmed/35820938 http://dx.doi.org/10.1186/s12974-022-02539-2

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