MYCN protein stability is a better prognostic indicator in neuroblastoma

OBJECTIVE: MYCN oncogene amplification is associated with treatment failure and poor prognosis in neuroblastoma. To date, most detection methods of MYCN focus on DNA copy numbers instead of protein expression, which is the real one performing biological function, for poor antibodies. The current inv...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Zhao, Jie, Zhang, Yingwen, Feng, Tianyue, Yv, Bo, Wang, Jing, Gao, Yijin, Yin, Minzhi, Tang, Jingyan, Li, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9277955/
https://www.ncbi.nlm.nih.gov/pubmed/35820898
http://dx.doi.org/10.1186/s12887-022-03449-1

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