Cargando…

The dynamics of t1 adenosine binding on human Argonaute 2: Understanding recognition with conformational selection

The control of expression in genetic regulation is a fundamental process for cell life. In RNA‐mediated silencing, human Argonaute‐2 protein (hAgo2) uses sequence information encoded in small RNAs (guide) to identify complementary sites in messenger RNAs (target) for repression. The specificity of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Rinaldi, Silvia, Colombo, Giorgio, Paladino, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278005/
https://www.ncbi.nlm.nih.gov/pubmed/35900022
http://dx.doi.org/10.1002/pro.4377