Cargando…

Role of Chromatin Modifying Complexes and Therapeutic Opportunities in Bladder Cancer

BACKGROUND: Chromatin modifying enzymes, mainly through post translational modifications, regulate chromatin architecture and by extension the underlying transcriptional kinetics in normal and malignant cells. Muscle invasive bladder cancer (MIBC) has a high frequency of alterations in chromatin mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meghani, Khyati, Folgosa Cooley, Lauren, Piunti, Andrea, Meeks, Joshua J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278011/ https://www.ncbi.nlm.nih.gov/pubmed/35898580 http://dx.doi.org/10.3233/BLC-211609

Ejemplares similares

Expression-based subtypes define pathologic response to neoadjuvant immune-checkpoint inhibitors in muscle-invasive bladder cancer
por: Robertson, A. Gordon, et al.
Publicado: (2023)

Hormonal Intensification Should Start at the Low-risk Stage in Metastatic Prostate Cancer
por: Jazayeri, Seyed Behzad, et al.
Publicado: (2022)

Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma
por: Piunti, Andrea, et al.
Publicado: (2022)

Narrative review of penile distal urethroplasties and suggestions for optimizing outcomes
por: Hofer, Matthias D., et al.
Publicado: (2021)

Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention
por: Uckelmann, Hannah J., et al.
Publicado: (2020)

Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
por: Hofer, Matthias D., et al.
Publicado: (2021)

Chromatin complex dependencies reveal targeting opportunities in leukemia
por: Najm, Fadi J., et al.
Publicado: (2023)

Anti-TNF agents and potential effects on male fertility: are men being counseled?
por: Cooley, Lauren Folgosa, et al.
Publicado: (2020)

Senescence and cancer — role and therapeutic opportunities
por: Schmitt, Clemens A., et al.
Publicado: (2022)

SWI/SNF chromatin remodeling complex and glucose metabolism are deregulated in advanced bladder cancer
por: Stachowiak, Malgorzata, et al.
Publicado: (2020)

The Nature of Actin-Family Proteins in Chromatin-Modifying Complexes
por: Klages-Mundt, Naeh L., et al.
Publicado: (2018)

The emerging role of ISWI chromatin remodeling complexes in cancer
por: Li, Yanan, et al.
Publicado: (2021)

The Emerging Role of Chromatin Remodeling Complexes in Ovarian Cancer
por: Vaicekauskaitė, Ieva, et al.
Publicado: (2022)

The Role of DNA/Histone Modifying Enzymes and Chromatin Remodeling Complexes in Testicular Germ Cell Tumors
por: Lobo, João, et al.
Publicado: (2018)

Approaches to Study Native Chromatin-Modifying Complex Activities and Functions
por: Galloy, Maxime, et al.
Publicado: (2021)

The BBN model: a mouse bladder cancer model featuring basal-subtype gene expression and MLL3/MLL4 genetic disruption
por: Fantini, Damiano, et al.
Publicado: (2018)

Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in Drosophila gene expression and development
por: Li, Xuanying, et al.
Publicado: (2017)

Dipstick Urinalysis as a Test for Microhematuria and Occult Bladder Cancer
por: Matulewicz, Richard S., et al.
Publicado: (2017)

Chromatin Proteomics to Study Epigenetics — Challenges and Opportunities
por: van Mierlo, Guido, et al.
Publicado: (2021)

The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer
por: Hasan, Nesrin, et al.
Publicado: (2019)

Gut Microbiota in Colorectal Cancer: Biological Role and Therapeutic Opportunities
por: Pandey, Himani, et al.
Publicado: (2023)

Insights into the Role of Sialylation in Cancer Metastasis, Immunity, and Therapeutic Opportunity
por: Huang, Jianmei, et al.
Publicado: (2022)

The SAGA chromatin-modifying complex: the sum of its parts is greater than the whole
por: Soffers, Jelly H.M., et al.
Publicado: (2020)

Trimodality Treatment for Muscle-Invasive Bladder Cancer: An Institutional Experience
por: Polineni, Praneet, et al.
Publicado: (2021)

Chromatin regulators in retinoblastoma: Biological roles and therapeutic applications
por: Lee, Chunsik, et al.
Publicado: (2020)

Lumbrokinase/paclitaxel nanoparticle complex: potential therapeutic applications in bladder cancer
por: Hu, Bo, et al.
Publicado: (2018)

Editorial: Chromatin Stability and Dynamics: Targeting and Recruitment of Chromatin Modifiers
por: Farrona, Sara, et al.
Publicado: (2021)

Multiparametric cystoscopy: opportunities to enhance bladder cancer detection
por: Taylor, Jacob, et al.
Publicado: (2020)

(Nano)platforms in bladder cancer therapy: Challenges and opportunities
por: Ashrafizadeh, Milad, et al.
Publicado: (2022)

Increased B Cell ADAM10 in Allergic Patients and Th2 Prone Mice
por: Cooley, Lauren Folgosa, et al.
Publicado: (2015)

Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice
por: Cooley, Lauren Folgosa, et al.
Publicado: (2016)

Modifying the Non-muscle Invasive Bladder Cancer Immune Microenvironment for Optimal Therapeutic Response
por: Annels, Nicola E., et al.
Publicado: (2020)

Histone deacetylase inhibitor-induced cell death in bladder cancer is associated with chromatin modification and modifying protein expression: A proteomic approach
por: LI, QINGDI QUENTIN, et al.
Publicado: (2016)

MMSET: Role and Therapeutic Opportunities in Multiple Myeloma
por: Xie, Zhigang, et al.
Publicado: (2014)

Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes
por: Zapata, Luis, et al.
Publicado: (2017)

Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
por: Sharov, Grigory, et al.
Publicado: (2017)

Ovarian Cancer Stem Cells: Role in Metastasis and Opportunity for Therapeutic Targeting
por: Zong, Xingyue, et al.
Publicado: (2019)

Role of tumor microenvironment in the pathobiology of ovarian cancer: Insights and therapeutic opportunities
por: Ghoneum, Alia, et al.
Publicado: (2018)

Heat Shock Proteins and Ovarian Cancer: Important Roles and Therapeutic Opportunities
por: Hoter, Abdullah, et al.
Publicado: (2019)

Roles of miRNAs in Colorectal Cancer: Therapeutic Implications and Clinical Opportunities
por: Mehrgou, Amir, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2a8ifh1juklkd7i82jjud5rhb2