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Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition

Ovarian cancer is the most fatal tumor characterized by an abundance of tumor-associated macrophage (TAM) infiltrations in women. Functional TAMs, which mainly present M2-like phenotypes and perform key functions on tumor progress, have been considered an attractive target for ovarian cancer therapy...

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Detalles Bibliográficos
Autores principales: Chen, Huajiao, Huang, Sheng, Niu, Peiguang, Zhu, Yanting, Zhou, Jintuo, Jiang, Li, Li, Danyun, Shi, Daohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278033/
https://www.ncbi.nlm.nih.gov/pubmed/35860007
http://dx.doi.org/10.1016/j.omto.2022.06.009

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