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Quantification of mutant–allele expression at isoform level in cancer from RNA-seq data
Even though the role of DNA mutations in cancer is well recognized, current quantification of the RNA expression, performed either at gene or isoform level, typically ignores the mutation status. Standard methods for estimating allele-specific expression (ASE) consider gene-level expression, but the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278039/ https://www.ncbi.nlm.nih.gov/pubmed/35855322 http://dx.doi.org/10.1093/nargab/lqac052 |