Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction

BACKGROUND: While the adult mammalian heart undergoes only modest renewal through cardiomyocyte proliferation, boosting this process is considered a promising therapeutic strategy to repair cardiac injury. This study explored the role and mechanism of dual-specificity tyrosine regulated kinase 1A (D...

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Detalles Bibliográficos
Autores principales: Lan, Cong, Chen, Caiyu, Qu, Shuang, Cao, Nian, Luo, Hao, Yu, Cheng, Wang, Na, Xue, Yuanzheng, Xia, Xuewei, Fan, Chao, Ren, Hongmei, Yang, Yongjian, Jose, Pedro A., Xu, Zaicheng, Wu, Gengze, Zeng, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278077/
https://www.ncbi.nlm.nih.gov/pubmed/35810562
http://dx.doi.org/10.1016/j.ebiom.2022.104139

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