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Hyperammonaemia induces mitochondrial dysfunction and neuronal cell death

BACKGROUND & AIMS: In cirrhosis, astrocytic swelling is believed to be the principal mechanism of ammonia neurotoxicity leading to hepatic encephalopathy (HE). The role of neuronal dysfunction in HE is not clear. We aimed to explore the impact of hyperammonaemia on mitochondrial function in prim...

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Detalles Bibliográficos
Autores principales:	Angelova, Plamena R., Kerbert, Annarein J.C., Habtesion, Abeba, Hall, Andrew, Abramov, Andrey Y., Jalan, Rajiv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278080/ https://www.ncbi.nlm.nih.gov/pubmed/35845295 http://dx.doi.org/10.1016/j.jhepr.2022.100510

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