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A So-Far Overlooked Secondary Conformation State in the Binding Mode of SARS-CoV-2 Spike Protein to Human ACE2 and Its Conversion Rate Are Crucial for Estimating Infectivity Efficacy of the Underlying Virus Variant

Since its outbreak in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread with high transmission efficiency across the world, putting health care as well as economic systems under pressure. During the course of the pandemic, the originally identified SARS-CoV-2 variant has...

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Detalles Bibliográficos
Autores principales: Sevenich, Marc, van den Heuvel, Joop, Gering, Ian, Mohrlüder, Jeannine, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278102/
https://www.ncbi.nlm.nih.gov/pubmed/35674432
http://dx.doi.org/10.1128/jvi.00685-22

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