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Hepatitis B Virus X Protein Is Stabilized by the Deubiquitinating Enzyme VCPIP1 in a Ubiquitin-Independent Manner by Recruiting the 26S Proteasome Subunit PSMC3

Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide, and the viral X protein (HBx) is an etiological factor in HCC development. HBx is a high-turnover protein, but knowledge of the role of deubiquitinating enzymes (DUBs) in maintaining HBx homeost...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Zhang, Lu, Xu, Xiazhen, Zhang, Yi, Shi, Jiajian, Lin, Xu, Chen, Wannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278118/
https://www.ncbi.nlm.nih.gov/pubmed/35695579
http://dx.doi.org/10.1128/jvi.00611-22

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