Longitudinal Assessment of SARS-CoV-2-Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multicytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity

Cell-mediated immunity is critical for long-term protection against most viral infections, including coronaviruses. We studied 23 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected survivors over a 1-year post-symptom onset (PSO) interval by ex vivo cytokine enzyme-linked immunoso...

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Detalles Bibliográficos
Autores principales: Lin, Jonah, Law, Ryan, Korosec, Chapin S., Zhou, Christine, Koh, Wan Hon, Ghaemi, Mohammad Sajjad, Samaan, Philip, Ooi, Hsu Kiang, Matveev, Vitaliy, Yue, FengYun, Gingras, Anne-Claude, Estacio, Antonio, Buchholz, Megan, Cheatley, Patti Lou, Mohammadi, Avid, Kaul, Rupert, Pavinski, Katerina, Mubareka, Samira, McGeer, Allison J., Leis, Jerome A., Heffernan, Jane M., Ostrowski, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278147/
https://www.ncbi.nlm.nih.gov/pubmed/35699447
http://dx.doi.org/10.1128/jvi.00509-22

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