Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis

Liver fibrosis occurs following inflammation triggered by the integrated actions of activated liver-resident macrophages (Kupffer cells) and hepatic stellate cells (HSCs), and the multiplicity of these mechanisms complicates drug therapy. Here, we demonstrate that the selective bromodomain and extra...

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Detalles Bibliográficos
Autores principales: Fu, Rong, Zu, Shi-Jia, Liu, Yan-Jun, Li, Jia-Cheng, Dang, Wen-Zhen, Liao, Li-Ping, Liu, Li-Ping, Chen, Pan-Yu, Huang, He-Ming, Wu, Kang-Hui, Zhou, Bing, Pan, Qin, Luo, Cheng, Zhang, Yuan-Yuan, Li, Guang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278415/
https://www.ncbi.nlm.nih.gov/pubmed/35499161
http://dx.doi.org/10.1080/21655979.2022.2066756

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