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MCL-1 is a clinically targetable vulnerability in breast cancer

Pro-survival members of the BCL-2 family, including MCL-1, are emerging as important proteins during the development and therapeutic response of solid tumors. Notably, high levels of MCL-1 occur in breast cancer, where functional dependency has been demonstrated using cell lines and mouse models. Th...

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Detalles Bibliográficos
Autores principales: Winder, Matthew L, Campbell, Kirsteen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278428/
https://www.ncbi.nlm.nih.gov/pubmed/35349392
http://dx.doi.org/10.1080/15384101.2022.2054096