Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinomas, with high mortality and poor prognoses worldwide. Succinate dehydrogenase (SDH) consists of four nuclear-encoded subunits and it is the only complex involved in both the tricarboxylic acid (TCA) cycle and oxidati...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Zhou, Yi, Li, Yanchun, Hu, Wanye, Yuan, Chen, Chen, Shida, Ye, Gaoqi, Chen, Yuzhou, Wu, Yunyi, Liu, Jing, Wang, Ying, Du, Jing, Tong, Xiangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278435/
https://www.ncbi.nlm.nih.gov/pubmed/35510387
http://dx.doi.org/10.1080/21655979.2022.2062537

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