Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma

Immunohistochemical markers have been frequently utilized as a diagnostic tool in pathology to help in diagnosing malignancy of unknown primary sites. In previous cases, the immunohistological expression of cytokeratin 7 (CK7), Napsin A, and thyroid transcription factor-1 (TTF-1) has helped identify...

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Detalles Bibliográficos
Autores principales: Malone, Mercedes, Bray, Christopher, Liu, Xiaolong Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278462/
https://www.ncbi.nlm.nih.gov/pubmed/35847168
http://dx.doi.org/10.7759/cureus.26782
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author Malone, Mercedes
Bray, Christopher
Liu, Xiaolong Sean
author_facet Malone, Mercedes
Bray, Christopher
Liu, Xiaolong Sean
author_sort Malone, Mercedes
collection PubMed
description Immunohistochemical markers have been frequently utilized as a diagnostic tool in pathology to help in diagnosing malignancy of unknown primary sites. In previous cases, the immunohistological expression of cytokeratin 7 (CK7), Napsin A, and thyroid transcription factor-1 (TTF-1) has helped identify and diagnose primary malignancy as originating from the lung. This case report describes an elderly woman with a liver metastasis consistent with a lung primary and illustrates the utility and importance of tissue-specific markers as a diagnostic tool in the evaluation of unknown primary tumors.
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spelling pubmed-92784622022-07-14 Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma Malone, Mercedes Bray, Christopher Liu, Xiaolong Sean Cureus Internal Medicine Immunohistochemical markers have been frequently utilized as a diagnostic tool in pathology to help in diagnosing malignancy of unknown primary sites. In previous cases, the immunohistological expression of cytokeratin 7 (CK7), Napsin A, and thyroid transcription factor-1 (TTF-1) has helped identify and diagnose primary malignancy as originating from the lung. This case report describes an elderly woman with a liver metastasis consistent with a lung primary and illustrates the utility and importance of tissue-specific markers as a diagnostic tool in the evaluation of unknown primary tumors. Cureus 2022-07-12 /pmc/articles/PMC9278462/ /pubmed/35847168 http://dx.doi.org/10.7759/cureus.26782 Text en Copyright © 2022, Malone et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Malone, Mercedes
Bray, Christopher
Liu, Xiaolong Sean
Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma
title Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma
title_full Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma
title_fullStr Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma
title_full_unstemmed Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma
title_short Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma
title_sort diagnosis of the primary tumor site in the case of liver metastatic carcinoma
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278462/
https://www.ncbi.nlm.nih.gov/pubmed/35847168
http://dx.doi.org/10.7759/cureus.26782
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AT braychristopher diagnosisoftheprimarytumorsiteinthecaseoflivermetastaticcarcinoma
AT liuxiaolongsean diagnosisoftheprimarytumorsiteinthecaseoflivermetastaticcarcinoma

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