Cargando…

Palladium-Catalyzed Access to Benzocyclobutenone-Derived Ketonitrones via C(sp(2))–H Functionalization

[Image: see text] The palladium-catalyzed C(sp(2))–H functionalization of bromoaryl aldonitrones leading to benzocyclobutenone-derived ketonitrones is described. This method allows for the preparation of a wide range of strained, four-membered ketonitrones with broad functional group tolerance. Down...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brześkiewicz, Jakub, Loska, Rafał
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278523/ https://www.ncbi.nlm.nih.gov/pubmed/35613705 http://dx.doi.org/10.1021/acs.orglett.2c01317

Ejemplares similares

Rh-catalyzed reagent-free ring expansion of cyclobutenones and benzocyclobutenones
por: Chen, Peng-hao, et al.
Publicado: (2015)

Deconstructive Synthesis of Bridged and Fused Rings via Transition-Metal-Catalyzed “Cut-and-Sew” Reactions of Benzocyclobutenones and Cyclobutanones
por: Xue, Yibin, et al.
Publicado: (2022)

Synthesis of aza-quaternary centers via Pictet–Spengler reactions of ketonitrones
por: Lynch-Colameta, Tessa, et al.
Publicado: (2021)

Synthesis of spirocyclic Δ(4)-isoxazolines via [3 + 2] cycloaddition of indanone-derived ketonitrones with alkynes
por: Liu, Yilin, et al.
Publicado: (2021)

Palladium-catalyzed regio- and enantioselective migratory allylic C(sp(3))-H functionalization
por: Chen, Ye-Wei, et al.
Publicado: (2021)

Palladium-Catalyzed Direct C=H Functionalization of Benzoquinone**
por: Walker, Sarah E, et al.
Publicado: (2014)

Access to indolines from primary phenylethylamines by an unexpected palladium-catalyzed C–H functionalization process
por: Mancinelli, Andrea, et al.
Publicado: (2019)

Modular synthesis of dihydro-isoquinolines: palladium-catalyzed sequential C(sp(2))–H and C(sp(3))–H bond activation
por: Liu, Weidong, et al.
Publicado: (2015)

Palladium-catalyzed intramolecular enantioselective C(sp(3))–H insertion of donor/donor carbenes
por: Li, Wendeng, et al.
Publicado: (2022)

Synthesis of phenanthridines via palladium-catalyzed picolinamide-directed sequential C–H functionalization
por: Pearson, Ryan, et al.
Publicado: (2013)

Enantioselective amine α-functionalization via palladium catalyzed C–H arylation of thioamides
por: Jain, Pankaj, et al.
Publicado: (2016)

Palladium-Catalyzed Transannular C–H Functionalization of Alicyclic Amines
por: Topczewski, Joseph J., et al.
Publicado: (2016)

Palladium-catalyzed dual C–H or N–H functionalization of unfunctionalized indole derivatives with alkenes and arenes
por: Broggini, Gianluigi, et al.
Publicado: (2012)

Continuous‐Flow Synthesis and Derivatization of Aziridines through Palladium‐Catalyzed C(sp(3))−H Activation
por: Zakrzewski, Jacek, et al.
Publicado: (2016)

Palladium-catalyzed benzylic C(sp(3))–H carbonylative arylation of azaarylmethyl amines with aryl bromides
por: Zhao, Haoqiang, et al.
Publicado: (2021)

Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp(3))–H allylation of 4-alkylpyridines
por: Wasfy, Nour, et al.
Publicado: (2020)

Access to 1-amino-3,4-dihydroisoquinolines via palladium-catalyzed C–H bond aminoimidoylation reaction from functionalized isocyanides
por: Xiong, Zhuang, et al.
Publicado: (2019)

Palladium(II)-Catalyzed Regioselective Ortho Arylation of sp(2) C—H Bonds of N-Aryl-2-amino Pyridine Derivatives
por: Koley, Moumita, et al.
Publicado: (2012)

Palladium(0)-catalyzed asymmetric C(sp(3))–H arylation using a chiral binol-derived phosphate and an achiral ligand
por: Yang, Lei, et al.
Publicado: (2017)

Palladium‐Catalyzed PIDA‐Mediated δ‐C(sp(3))−H Acetoxylation of Amino Acid Derivatives: Overriding Competitive Intramolecular Amination
por: Martínez‐Mingo, Mario, et al.
Publicado: (2022)

Rapid Access to Spirocyclized Indolenines via Palladium-Catalyzed Cascade Reactions of Tryptamine Derivatives and Propargyl Carbonate
por: Montgomery, Thomas D., et al.
Publicado: (2014)

Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones
por: Xu, Peng-Wei, et al.
Publicado: (2017)

Synthesis of ethoxy dibenzooxaphosphorin oxides through palladium-catalyzed C(sp(2))–H activation/C–O formation
por: Shin, Seohyun, et al.
Publicado: (2014)

Palladium-catalyzed ortho-halogenations of acetanilides with N-halosuccinimides via direct sp(2) C–H bond activation in ball mills
por: Liu, Zi, et al.
Publicado: (2018)

Palladium-catalyzed ligand-promoted site-selective cyanomethylation of unactivated C(sp(3))–H bonds with acetonitrile
por: Liu, Yongbing, et al.
Publicado: (2016)

Palladium-catalyzed dehydrogenative C–H cyclization for isoindolinone synthesis
por: Abe, Masahiro, et al.
Publicado: (2021)

Directed Palladium Catalyzed C−H (Ethoxycarbonyl)difluoromethylthiolation Reactions
por: Doche, Floriane, et al.
Publicado: (2022)

Oxalyl amide assisted palladium-catalyzed synthesis of pyrrolidones via carbonylation of γ-C(sp(3))–H bonds of aliphatic amine substrates
por: Wang, Chao, et al.
Publicado: (2015)

Strategies for palladium-catalyzed non-directed and directed C-H bond functionalization
por: Kapdi, Anant R, et al.
Publicado: (2017)

Silacyclization through palladium-catalyzed intermolecular silicon-based C(sp(2))–C(sp(3)) cross-coupling
por: Qin, Ying, et al.
Publicado: (2021)

Palladium(II)-Catalyzed Enantioselective C(sp(3))–H Activation Using a Chiral Hydroxamic Acid Ligand
por: Xiao, Kai-Jiong, et al.
Publicado: (2014)

Macrocyclization of peptidoarylacetamides with self-assembly properties through late-stage palladium-catalyzed C(sp(2))▬H olefination
por: Tan, Jiantao, et al.
Publicado: (2019)

Palladium-Catalyzed Arylation of C(sp(2))–H Bonds with 2-(1-Methylhydrazinyl)pyridine as the Bidentate Directing Group
por: Wei, Jian, et al.
Publicado: (2021)

Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
por: Zhang, Chengwei, et al.
Publicado: (2016)

Palladium Catalyzed Allylic C-H Alkylation: A Mechanistic Perspective
por: Engelin, Casper Junker, et al.
Publicado: (2011)

Palladium-Catalyzed Nondirected Late-Stage C–H Deuteration of Arenes
por: Farizyan, Mirxan, et al.
Publicado: (2021)

Palladium‐Catalyzed para‐C−H Arylation of Anilines with Aromatic Halides
por: Lichte, Dominik, et al.
Publicado: (2022)

A palladium-catalyzed C–H functionalization route to ketones via the oxidative coupling of arenes with carbon monoxide
por: Levesque, Taleah M., et al.
Publicado: (2020)

Palladium-catalyzed enantioselective alkenylation of alkenylbenzene derivatives
por: Chen, Zhi-Min, et al.
Publicado: (2019)

Photocatalytic Palladium-Catalyzed Fluoroalkylation of Styrene Derivatives
por: Adamik, Réka, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bgttbh1hgol3c69otkkidvmgov