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Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation
PURPOSE: To investigate the dose‐sensitometric response of extended dose range (EDR2) films to scanning carbon‐ion beams and to evaluate the applications of the obtained response curves to carbon‐ion dose distributions. METHODS: EDR2 films were irradiated by mono‐energetic scanning carbon‐ion beams...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278678/ https://www.ncbi.nlm.nih.gov/pubmed/35594015 http://dx.doi.org/10.1002/acm2.13636 |
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author | Wang, Weiwei Deng, Yu Huang, Zhijie |
author_facet | Wang, Weiwei Deng, Yu Huang, Zhijie |
author_sort | Wang, Weiwei |
collection | PubMed |
description | PURPOSE: To investigate the dose‐sensitometric response of extended dose range (EDR2) films to scanning carbon‐ion beams and to evaluate the applications of the obtained response curves to carbon‐ion dose distributions. METHODS: EDR2 films were irradiated by mono‐energetic scanning carbon‐ion beams with different doses to obtain sensitometric curves at different integrated depth doses (DDDs). Six different DDDs were generated by using a proper buildup for each mono‐energetic beam and were used to investigate the energy dependence. The sensitometric curves were obtained by fitting the net optical density (netOD) to dose at different DDDs. The dose difference between the value converted from the netOD and that calculated in the treatment planning system (TPS) was investigated to evaluate the application scope of the sensitometric curve. RESULTS: Digitizing the EDR2 film with a resolution of 0.36 (72 dpi) provided a good signal‐to‐noise ratio, and the sensitometric curve was linear at all DDDs of clinically relevant incident kinetic energies in the netOD range of 0.02–1.70 for carbon‐ion film dosimetry. The factors used to convert the netOD to absorbed dose were expressed as a linear function of DDDs, with which the depth dose difference between converted and TPS was less than 3% in the proximal area for incident kinetic energies lower than 307.5 MeV/u. CONCLUSION: The EDR2 film is a feasible tool for scanning carbon‐ion beam profile measurements by directly evaluating the netOD distribution with proper digitizing resolution and netOD range. By applying the conversion factors, the EDR2 film can also be employed to perform the percentage depth dose consistency checking and linear energy transfer comparison of carbon‐ion lower than 307.5 MeV/u. |
format | Online Article Text |
id | pubmed-9278678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92786782022-07-15 Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation Wang, Weiwei Deng, Yu Huang, Zhijie J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: To investigate the dose‐sensitometric response of extended dose range (EDR2) films to scanning carbon‐ion beams and to evaluate the applications of the obtained response curves to carbon‐ion dose distributions. METHODS: EDR2 films were irradiated by mono‐energetic scanning carbon‐ion beams with different doses to obtain sensitometric curves at different integrated depth doses (DDDs). Six different DDDs were generated by using a proper buildup for each mono‐energetic beam and were used to investigate the energy dependence. The sensitometric curves were obtained by fitting the net optical density (netOD) to dose at different DDDs. The dose difference between the value converted from the netOD and that calculated in the treatment planning system (TPS) was investigated to evaluate the application scope of the sensitometric curve. RESULTS: Digitizing the EDR2 film with a resolution of 0.36 (72 dpi) provided a good signal‐to‐noise ratio, and the sensitometric curve was linear at all DDDs of clinically relevant incident kinetic energies in the netOD range of 0.02–1.70 for carbon‐ion film dosimetry. The factors used to convert the netOD to absorbed dose were expressed as a linear function of DDDs, with which the depth dose difference between converted and TPS was less than 3% in the proximal area for incident kinetic energies lower than 307.5 MeV/u. CONCLUSION: The EDR2 film is a feasible tool for scanning carbon‐ion beam profile measurements by directly evaluating the netOD distribution with proper digitizing resolution and netOD range. By applying the conversion factors, the EDR2 film can also be employed to perform the percentage depth dose consistency checking and linear energy transfer comparison of carbon‐ion lower than 307.5 MeV/u. John Wiley and Sons Inc. 2022-05-20 /pmc/articles/PMC9278678/ /pubmed/35594015 http://dx.doi.org/10.1002/acm2.13636 Text en © 2022 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Wang, Weiwei Deng, Yu Huang, Zhijie Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation |
title | Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation |
title_full | Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation |
title_fullStr | Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation |
title_full_unstemmed | Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation |
title_short | Experimental dosimetry of EDR2 films in scanning carbon‐ion irradiation |
title_sort | experimental dosimetry of edr2 films in scanning carbon‐ion irradiation |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278678/ https://www.ncbi.nlm.nih.gov/pubmed/35594015 http://dx.doi.org/10.1002/acm2.13636 |
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