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Reshaping the Preterm Heart: Shifting Cardiac Renin-Angiotensin System Towards Cardioprotection in Rats Exposed to Neonatal High-Oxygen Stress
BACKGROUND: Approximately 10% of infants are born preterm. Preterm birth leads to short and long-term changes in cardiac shape and function. By using a rat model of neonatal high-oxygen (80%O(2)) exposure, mimicking the premature hyperoxic transition to the extrauterine environment, we revealed a ma...
Autores principales: | Bertagnolli, Mariane, Dartora, Daniela R., Lamata, Pablo, Zacur, Ernesto, Mai-Vo, Thuy-An, He, Ying, Beauchamp, Léonie, Lewandowski, Adam J., Cloutier, Anik, Sutherland, Megan R., Santos, Robson A.S., Nuyt, Anne Monique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278707/ https://www.ncbi.nlm.nih.gov/pubmed/35588210 http://dx.doi.org/10.1161/HYPERTENSIONAHA.122.19115 |
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