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Polygenic score for Alzheimer’s disease identifies differential atrophy in hippocampal subfield volumes

Hippocampal subfield atrophy is a prime structural change in the brain, associated with cognitive aging and neurodegenerative diseases such as Alzheimer’s disease. Recent developments in genome-wide association studies (GWAS) have identified genetic loci that characterize the risk of hippocampal vol...

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Detalles Bibliográficos
Autores principales: Kannappan, Balaji, Gunasekaran, Tamil Iniyan, te Nijenhuis, Jan, Gopal, Muthu, Velusami, Deepika, Kothandan, Gugan, Lee, Kun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278752/
https://www.ncbi.nlm.nih.gov/pubmed/35830443
http://dx.doi.org/10.1371/journal.pone.0270795