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Cis-regulatory chromatin loops analysis identifies GRHL3 as a master regulator of surface epithelium commitment

Understanding the regulatory network of cell fate acquisition remains a major challenge. Using the induction of surface epithelium (SE) from human embryonic stem cells as a paradigm, we show that the dynamic changes in morphology-related genes (MRGs) closely correspond to SE fate transitions. The ma...

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Detalles Bibliográficos
Autores principales:	Huang, Huaxing, Liu, Jiafeng, Li, Mingsen, Guo, Huizhen, Zhu, Jin, Zhu, Liqiong, Wu, Siqi, Mo, Kunlun, Huang, Ying, Tan, Jieying, Chen, Chaoqun, Wang, Bofeng, Yu, Yankun, Wang, Li, Liu, Yizhi, Ouyang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278850/ https://www.ncbi.nlm.nih.gov/pubmed/35857527 http://dx.doi.org/10.1126/sciadv.abo5668

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