Cargando…

LncRNA MBNL1-AS1 represses gastric cancer progression via the TGF-β pathway by modulating miR-424-5p/Smad7 axis

Studies over the past decades have implicated lncRNAs in promoting the development, migration and invasion of gastric cancer (GC). However, the role and mechanism of lncRNA MBNL1-AS1 in GC promotion are poorly understood. In this research, qRT-PCR showed that MBNL1-AS1 was down-regulated in GC tissu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Jiewen, Chen, Dawei, Ruan, Yi, Tian, Yuan, Lv, Kaiji, Zhou, Xinhua, Ying, Dongjian, Lu, Yeting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278977/ https://www.ncbi.nlm.nih.gov/pubmed/35311623 http://dx.doi.org/10.1080/21655979.2022.2037921

Ejemplares similares

LncRNA MBNL1-AS1 Represses Proliferation and Cancer Stem-Like Properties of Breast Cancer through MBNL1-AS1/ZFP36/CENPA Axis
por: Ding, Yu, et al.
Publicado: (2022)

LncRNA LINC01857 drives pancreatic adenocarcinoma progression via modulating miR-19a-3p/SMOC2
por: Lu, Yeting, et al.
Publicado: (2022)

Identification of MBNL1 and MBNL3 domains required for splicing activation and repression
por: Grammatikakis, Ioannis, et al.
Publicado: (2011)

LncRNA MBNL1‐AS1 represses cell proliferation and enhances cell apoptosis via targeting miR‐135a‐5p/PHLPP2/FOXO1 axis in bladder cancer
por: Wei, Xiaosong, et al.
Publicado: (2019)

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3
por: Gooding, Clare, et al.
Publicado: (2013)

NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis
por: Tang, Tian, et al.
Publicado: (2021)

LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling
por: Zhang, Yiming, et al.
Publicado: (2023)

Knockdown of lncRNA PVT1 Inhibits Glioma Progression by Regulating miR-424 Expression
por: Han, Yanjie, et al.
Publicado: (2019)

Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript
por: Konieczny, Patryk, et al.
Publicado: (2017)

Mbnl1 and Mbnl2 regulate brain structural integrity in mice
por: Sta Maria, Naomi S., et al.
Publicado: (2021)

LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
por: Cao, Feng, et al.
Publicado: (2019)

The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1
por: Welte, Thomas, et al.
Publicado: (2019)

TGF-β/SMAD4-Regulated LncRNA-LINP1 Inhibits Epithelial-Mesenchymal Transition in Lung Cancer
por: Zhang, Chong, et al.
Publicado: (2018)

Qingjie Fuzheng Granule Inhibited the Migration and Invasion of Colorectal Cancer Cells by Regulating the lncRNA ANRIL/let-7a/TGF-β1/Smad Axis
por: Zhang, Ling, et al.
Publicado: (2020)

lncRNA TINCR attenuates the proliferation and invasion, and enhances the apoptosis of cutaneous malignant melanoma cells by regulating the miR-424-5p/LATS1 axis
por: Han, Xuemei, et al.
Publicado: (2021)

TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-β signaling
por: Guca, Ewelina, et al.
Publicado: (2018)

LncRNA MBNL1-AS1 Suppresses Cell Proliferation and Metastasis of Pancreatic Adenocarcinoma through Targeting Carcinogenic miR-301b-3p
por: Sulidankazha, Chouman, et al.
Publicado: (2023)

Alternative splicing mediates the compensatory upregulation of MBNL2 upon MBNL1 loss-of-function
por: Nitschke, Larissa, et al.
Publicado: (2023)

LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis
por: Gao, Qin, et al.
Publicado: (2021)

LncRNA-Gm9866 promotes liver fibrosis by activating TGFβ/Smad signaling via targeting Fam98b
por: Liao, Xiaomin, et al.
Publicado: (2023)

Down-Regulation of lncRNA MBNL1-AS1 Promotes Tumor Stem Cell-like Characteristics and Prostate Cancer Progression through miR-221-3p/CDKN1B/C-myc Axis
por: Liu, Ji, et al.
Publicado: (2022)

L-Glutamine alleviates osteoarthritis by regulating lncRNA-NKILA expression through the TGF-β1/SMAD2/3 signalling pathway
por: Ma, Xiao, et al.
Publicado: (2022)

The long-noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells
por: Zhang, Jinqiang, et al.
Publicado: (2020)

RNA Splicing Is Responsive to MBNL1 Dose
por: Jog, Sonali P., et al.
Publicado: (2012)

LncRNA-AWPPH activates TGF-β1 in colorectal adenocarcinoma
por: Liu, Chengcong, et al.
Publicado: (2019)

LncRNA np_5318 promotes renal ischemia-reperfusion injury through the TGF-β/Smad signaling pathway
por: Lu, Jing, et al.
Publicado: (2020)

lncRNA NEAT1/miR‐495‐3p regulates angiogenesis in burn sepsis through the TGF‐β1 and SMAD signaling pathways
por: Meng, Yanbin, et al.
Publicado: (2023)

miR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-β signaling pathway
por: Wei, Song, et al.
Publicado: (2016)

CircLMTK2 Silencing Attenuates Gemcitabine Resistance in Pancreatic Cancer by Sponging miR-485-5p and to Target PAK1
por: Lu, Yeting, et al.
Publicado: (2022)

Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy
por: Chen, Guiying, et al.
Publicado: (2016)

LncRNA MALAT1 Modulates TGF-β1-Induced EMT in Keratinocyte
por: Zhang, Liping, et al.
Publicado: (2021)

Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy
por: Lee, Kuang-Yung, et al.
Publicado: (2022)

Correction: miR-424-5p promotes proliferation of gastric cancer by targeting Smad3 through TGF-β signaling pathway
por: Wei, Song, et al.
Publicado: (2017)

TGF-β1 upregulates the expression of lncRNA-ATB to promote atherosclerosis
por: Yu, Huapeng, et al.
Publicado: (2019)

LncRNA CCAT2, involving miR-34a/TGF-β1/Smad4 signaling, regulate hepatic stellate cells proliferation
por: Gao, Haibing, et al.
Publicado: (2022)

Increased lncRNA ABHD11-AS1 represses the malignant phenotypes of bladder cancer
por: Chen, Mingwei, et al.
Publicado: (2017)

Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB1
por: Yi, Erkang, et al.
Publicado: (2023)

lncRNA CCAT2 Enhanced Resistance of Glioma Cells Against Chemodrugs by Disturbing the Normal Function of miR-424
por: Ding, Jun, et al.
Publicado: (2020)

(CTG)n repeat-mediated dysregulation of MBNL1 and MBNL2 expression during myogenesis in DM1 occurs already at the myoblast stage
por: André, Laurène M., et al.
Publicado: (2019)

The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis
por: Xu, Jin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gqgedpk2hfviataq3k0nqfik90