p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB

The microenvironment of lymphoid organs is central to the pathogenesis of chronic lymphocytic leukemia (CLL). Within it, tumor cells find a favourable niche to escape immunosurveillance and acquire pro-survival signals. We have previously reported that a CLL-associated defect in the expression of th...

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Detalles Bibliográficos
Autores principales: Tatangelo, Vanessa, Boncompagni, Gioia, Capitani, Nagaja, Lopresti, Ludovica, Manganaro, Noemi, Frezzato, Federica, Visentin, Andrea, Trentin, Livio, Baldari, Cosima T., Patrussi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278989/
https://www.ncbi.nlm.nih.gov/pubmed/35847884
http://dx.doi.org/10.3389/fonc.2022.877495

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