Perilipin 2 Protects against Lipotoxicity-Induced Islet Fibrosis by Inducing Islet Stellate Cell Activation Phenotype Changes

AIMS: We explored whether and how perilipin 2 (Plin2) protected islets against lipotoxicity-induced islet dysfunction by regulating islet stellate cells (ISCs) activation. METHODS: Six-week-old male rats were given a high-fat diet or a control diet for 28 weeks. Glucose metabolic phenotypes were ass...

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Detalles Bibliográficos
Autores principales: Zhou, Yunting, Wang, Yuming, Ni, Chengming, Wang, Huiying, Zhou, Junming, Wan, Bingying, Li, Huiqin, Li, Fengfei, Huang, Rong, Xu, Wei, Shan, Ting, Cai, Tingting, Kong, Xiaoceng, Liu, Bingli, Liu, Xiaomei, Sun, Zilin, Ma, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279040/
https://www.ncbi.nlm.nih.gov/pubmed/35845956
http://dx.doi.org/10.1155/2022/4581405

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