Exosomal miR-27b-3p Derived from Hypoxic Cardiac Microvascular Endothelial Cells Alleviates Rat Myocardial Ischemia/Reperfusion Injury through Inhibiting Oxidative Stress-Induced Pyroptosis via Foxo1/GSDMD Signaling

BACKGROUND: Exosomes derived from cardiac microvascular endothelial cells (CMECs) under hypoxia can mediate cardiac repair functions and alleviate pyroptosis and oxidative stress during ischemia-reperfusion (I/R) injury. This study is aimed at investigating the effect and mechanism of miR-27b-3p und...

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Detalles Bibliográficos
Autores principales: Zhang, Baojian, Sun, Chao, Liu, Yaozhong, Bai, Fan, Tu, Tao, Liu, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279077/
https://www.ncbi.nlm.nih.gov/pubmed/35847592
http://dx.doi.org/10.1155/2022/8215842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279077/
https://www.ncbi.nlm.nih.gov/pubmed/35847592
http://dx.doi.org/10.1155/2022/8215842

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