A sequence-based global map of regulatory activity for deciphering human genetics

Epigenomic profiling has enabled large-scale identification of regulatory elements, yet we still lack a systematic mapping from any sequence or variant to regulatory activities. We address this challenge with Sei, a framework for integrating human genetics data with sequence information to discover...

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Detalles Bibliográficos
Autores principales: Chen, Kathleen M., Wong, Aaron K., Troyanskaya, Olga G., Zhou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279145/
https://www.ncbi.nlm.nih.gov/pubmed/35817977
http://dx.doi.org/10.1038/s41588-022-01102-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279145/
https://www.ncbi.nlm.nih.gov/pubmed/35817977
http://dx.doi.org/10.1038/s41588-022-01102-2

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