Transgenic overexpression of microRNA-30d in pancreatic beta-cells progressively regulates beta-cell function and identity

Abnormal microRNA functions are closely associated with pancreatic β-cell loss and dysfunction in type 2 diabetes. Dysregulation of miR-30d has been reported in the individuals with diabetes. To study how miR-30d affects pancreatic β-cell functions, we generated two transgenic mouse lines that speci...

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Detalles Bibliográficos
Autores principales: Mao, Yiping, Schoenborn, Jacob, Wang, Zhihong, Chen, Xinqian, Matson, Katy, Mohan, Ramkumar, Zhang, Shungang, Tang, Xiaohu, Arunagiri, Anoop, Arvan, Peter, Tang, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279310/
https://www.ncbi.nlm.nih.gov/pubmed/35831364
http://dx.doi.org/10.1038/s41598-022-16174-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279310/
https://www.ncbi.nlm.nih.gov/pubmed/35831364
http://dx.doi.org/10.1038/s41598-022-16174-7

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