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Bivalent metal ions induce formation of α-synuclein fibril polymorphs with different cytotoxicities

α-Synuclein (α-Syn) aggregates are key components of intracellular inclusion bodies characteristic of Parkinson’s disease (PD) and other synucleinopathies. Metal ions have been considered as the important etiological factors in PD since their interactions with α-Syn alter the kinetics of fibrillatio...

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Detalles Bibliográficos
Autores principales:	Atarod, Deyhim, Mamashli, Fatemeh, Ghasemi, Atiyeh, Moosavi-Movahedi, Faezeh, Pirhaghi, Mitra, Nedaei, Hadi, Muronetz, Vladimir, Haertlé, Thomas, Tatzelt, Jörg, Riazi, Gholamhossein, Saboury, Ali Akbar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279330/ https://www.ncbi.nlm.nih.gov/pubmed/35831343 http://dx.doi.org/10.1038/s41598-022-15472-4

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