Cargando…
Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model
Understanding the immunological effects of chemotherapy is of great importance, especially now that we have entered an era where ever-increasing pre-clinical and clinical efforts are put into combining chemotherapy and immunotherapy to combat cancer. Single-cell RNA sequencing (scRNA-seq) has proved...
Autores principales: | Selvin, Tove, Fasterius, Erik, Jarvius, Malin, Fryknäs, Mårten, Larsson, Rolf, Andersson, Claes R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279337/ https://www.ncbi.nlm.nih.gov/pubmed/35831404 http://dx.doi.org/10.1038/s41598-022-16077-7 |
Ejemplares similares
-
Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death
por: Selvin, Tove, et al.
Publicado: (2023) -
Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma
por: Ek, Frida, et al.
Publicado: (2022) -
Mebendazole is unique among tubulin-active drugs in activating the MEK–ERK pathway
por: Andersson, Claes R., et al.
Publicado: (2020) -
Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition
por: Blom, Kristin, et al.
Publicado: (2019) -
Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance
por: Fryknäs, Mårten, et al.
Publicado: (2013)