Cargando…

Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis

Sepsis has affected millions of populations of all age groups, locations, and sexes worldwide. Immune systems, either innate or adaptive are dysregulated due to the infection. Various biomarkers are present to date, still sepsis is a primary cause of mortality. Globally, post-operative body infectio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohsin, Mohd, Singh, Prithvi, Khan, Salman, Verma, Amit Kumar, Jha, Rishabh, Alsahli, Mohammed A., Rahmani, Arshad Husain, Almatroodi, Saleh A., Alrumaihi, Faris, Kaprwan, Nisha, Dev, Kapil, Dohare, Ravins, Syed, Mansoor Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279366/ https://www.ncbi.nlm.nih.gov/pubmed/35831411 http://dx.doi.org/10.1038/s41598-022-16183-6

Ejemplares similares

Survival-Based Biomarker Module Identification Associated with Oral Squamous Cell Carcinoma (OSCC)
por: Singh, Prithvi, et al.
Publicado: (2021)

Exploring the role of miR-200 family in regulating CX3CR1 and CXCR1 in lung adenocarcinoma tumor microenvironment: implications for therapeutic intervention
por: Sharma, Archana, et al.
Publicado: (2023)

Combined Multiomics and In Silico Approach Uncovers PRKAR1A as a Putative Therapeutic Target in Multi-Organ Dysfunction Syndrome
por: Singh, Prithvi, et al.
Publicado: (2023)

Comprehensive Integrative Analysis Reveals the Association of KLF4 with Macrophage Infiltration and Polarization in Lung Cancer Microenvironment
por: Arora, Shweta, et al.
Publicado: (2021)

Unravelling the Role of miR-20b-5p, CCNB1, HMGA2 and E2F7 in Development and Progression of Non-Small Cell Lung Cancer (NSCLC)
por: Arora, Shweta, et al.
Publicado: (2020)

Transcriptomic analysis delineates potential signature genes and miRNAs associated with the pathogenesis of asthma
por: Singh, Prithvi, et al.
Publicado: (2020)

Inhibition of miRNA-34a Promotes M2 Macrophage Polarization and Improves LPS-Induced Lung Injury by Targeting Klf4
por: Khan, Mohd Junaid, et al.
Publicado: (2020)

Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection
por: Gupta, Sonam, et al.
Publicado: (2022)

Transcriptome Meta-Analysis Deciphers a Dysregulation in Immune Response-Associated Gene Signatures during Sepsis
por: Ahmad, Shaniya, et al.
Publicado: (2019)

Curcumin, an Active Constituent of Turmeric Spice: Implication in the Prevention of Lung Injury Induced by Benzo(a) Pyrene (BaP) in Rats
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Unravelling host-pathogen interactions: ceRNA network in SARS-CoV-2 infection (COVID-19)
por: Arora, Shweta, et al.
Publicado: (2020)

Role of Cytokines and Chemokines in NSCLC Immune Navigation and Proliferation
por: Ramachandran, Sowmya, et al.
Publicado: (2021)

6-Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine-Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti-Inflammatory Activity
por: Alsahli, Mohammed A., et al.
Publicado: (2021)

Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2022)

SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy
por: Rafat, Sahar, et al.
Publicado: (2022)

Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina
por: Kumar, Sunil, et al.
Publicado: (2021)

Identification of differentially expressed genes in small and non-small cell lung cancer based on meta-analysis of mRNA
por: Shriwash, Nitesh, et al.
Publicado: (2019)

Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management
por: Allemailem, Khaled S., et al.
Publicado: (2022)

Investigating the role of Kinesin family in lung adenocarcinoma via integrated bioinformatics approach
por: Tabassum, Gulnaz, et al.
Publicado: (2023)

spib is required for primitive myeloid development in Xenopus
por: Costa, Ricardo M. B., et al.
Publicado: (2008)

Network-based identification of signature genes KLF6 and SPOCK1 associated with oral submucous fibrosis
por: Singh, Prithvi, et al.
Publicado: (2020)

Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics
por: Allemailem, Khaled S, et al.
Publicado: (2021)

Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways
por: Almatroudi, Ahmad, et al.
Publicado: (2023)

Potential Antitumor Effects of Pomegranates and Its Ingredients
por: Rahmani, Arshad H., et al.
Publicado: (2017)

Protective Effects of Thymoquinone, an Active Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative Stress and Inflammation
por: Alzohairy, Mohammad A., et al.
Publicado: (2021)

Prognostic Significance of Vascular Endothelial Growth Factor (VEGF) and Her-2 Protein in the Genesis of Cervical Carcinoma
por: Rahmani, Arshad H., et al.
Publicado: (2018)

Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Autophagy Paradox of Cancer: Role, Regulation, and Duality
por: Verma, Amit Kumar, et al.
Publicado: (2021)

A Compendium of Perspectives on Diabetes: A Challenge for Sustainable Health in the Modern Era
por: Verma, Amit K, et al.
Publicado: (2021)

Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
por: Allemailem, Khaled S., et al.
Publicado: (2023)

Endoplasmic Reticulum Stress Provocation by Different Nanoparticles: An Innovative Approach to Manage the Cancer and Other Common Diseases
por: Khan, Amjad Ali, et al.
Publicado: (2020)

Correlation of NTRK1 Downregulation with Low Levels of Tumor-Infiltrating Immune Cells and Poor Prognosis of Prostate Cancer Revealed by Gene Network Analysis
por: Bagherabadi, Arash, et al.
Publicado: (2022)

The Potential Role of Apigenin in Cancer Prevention and Treatment
por: Rahmani, Arshad Husain, et al.
Publicado: (2022)

BCL-2 (-938C>A), BAX (-248G>A), and HER2 Ile655Val Polymorphisms and Breast Cancer Risk in Indian Population
por: Bhatt, Deepti, et al.
Publicado: (2021)

Association of Rheumatoid Arthritis with Diabetic Comorbidity: Correlating Accelerated Insulin Resistance to Inflammatory Responses in Patients
por: Verma, Amit K, et al.
Publicado: (2021)

Association Between CDKAL1, HHEX, CDKN2A/2B and IGF2BP2 Gene Polymorphisms and Susceptibility to Type 2 Diabetes in Uttarakhand, India
por: Verma, Amit K, et al.
Publicado: (2021)

Assessment and Management of Diabetic Patients During the COVID-19 Pandemic
por: Verma, Amit K, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sbtsaqjf39mbdeijusmldnhjkb