Monomeric prefusion structure of an extremophile gamete fusogen and stepwise formation of the postfusion trimeric state

Here, we study the gamete fusogen HAP2 from Cyanidioschyzon merolae (Cyani), an extremophile red algae that grows at acidic pH at 45 °C. HAP2 has a trimeric postfusion structure with similarity to viral class II fusion proteins, but its prefusion structure has been elusive. The crystal structure of...

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Detalles Bibliográficos
Autores principales: Feng, Juan, Dong, Xianchi, Su, Yang, Lu, Chafen, Springer, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279424/
https://www.ncbi.nlm.nih.gov/pubmed/35831325
http://dx.doi.org/10.1038/s41467-022-31744-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279424/
https://www.ncbi.nlm.nih.gov/pubmed/35831325
http://dx.doi.org/10.1038/s41467-022-31744-z

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