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Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions
Establishment of zoonotic viruses, causing pandemics like the Spanish flu and Covid-19, requires adaptation to human receptors. Pandemic influenza A viruses (IAV) that crossed the avian-human species barrier switched from binding avian-type α2-3-linked sialic acid (2-3Sia) to human-type 2-6Sia recep...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279479/ https://www.ncbi.nlm.nih.gov/pubmed/35831293 http://dx.doi.org/10.1038/s41467-022-31840-0 |