The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer

Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene expression plays an important role. CRC is curren...

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Autores principales: He, JinHua, Xi, NaiTe, Han, ZePing, Luo, WenFeng, Shen, Jian, Wang, ShengBo, Li, JianHao, Guo, ZhongHui, Cheng, HanWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279561/
https://www.ncbi.nlm.nih.gov/pubmed/35846270
http://dx.doi.org/10.3389/fendo.2022.875442
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author He, JinHua
Xi, NaiTe
Han, ZePing
Luo, WenFeng
Shen, Jian
Wang, ShengBo
Li, JianHao
Guo, ZhongHui
Cheng, HanWei
author_facet He, JinHua
Xi, NaiTe
Han, ZePing
Luo, WenFeng
Shen, Jian
Wang, ShengBo
Li, JianHao
Guo, ZhongHui
Cheng, HanWei
author_sort He, JinHua
collection PubMed
description Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene expression plays an important role. CRC is currently diagnosed via endoscopy combined with tissue biopsy. Compared with tissue biopsy, liquid biopsy technology has received increasingly more attention and applications in the field of molecular detection due to its non-invasive, safe, comprehensive, and real-time dynamic nature. This review article discusses the application and limitations of current liquid biopsy analytes in the diagnosis, treatment, and prognosis of CRC, as well as directions for their future development.
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spelling pubmed-92795612022-07-15 The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer He, JinHua Xi, NaiTe Han, ZePing Luo, WenFeng Shen, Jian Wang, ShengBo Li, JianHao Guo, ZhongHui Cheng, HanWei Front Endocrinol (Lausanne) Endocrinology Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene expression plays an important role. CRC is currently diagnosed via endoscopy combined with tissue biopsy. Compared with tissue biopsy, liquid biopsy technology has received increasingly more attention and applications in the field of molecular detection due to its non-invasive, safe, comprehensive, and real-time dynamic nature. This review article discusses the application and limitations of current liquid biopsy analytes in the diagnosis, treatment, and prognosis of CRC, as well as directions for their future development. Frontiers Media S.A. 2022-06-30 /pmc/articles/PMC9279561/ /pubmed/35846270 http://dx.doi.org/10.3389/fendo.2022.875442 Text en Copyright © 2022 He, Xi, Han, Luo, Shen, Wang, Li, Guo and Cheng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
He, JinHua
Xi, NaiTe
Han, ZePing
Luo, WenFeng
Shen, Jian
Wang, ShengBo
Li, JianHao
Guo, ZhongHui
Cheng, HanWei
The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
title The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
title_full The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
title_fullStr The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
title_full_unstemmed The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
title_short The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
title_sort role of liquid biopsy analytes in diagnosis, treatment and prognosis of colorectal cancer
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279561/
https://www.ncbi.nlm.nih.gov/pubmed/35846270
http://dx.doi.org/10.3389/fendo.2022.875442
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