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Total Flavonoids of Drynariae Rhizoma Improve Glucocorticoid-Induced Osteoporosis of Rats: UHPLC-MS-Based Qualitative Analysis, Network Pharmacology Strategy and Pharmacodynamic Validation

BACKGROUND: Glucocorticoid-induced osteoporosis (GIOP) is a common form of secondary osteoporosis caused by the protracted or a large dosage of glucocorticoids (GCs). Total flavonoids of Drynariae rhizoma (TFDR) have been widely used in treating postmenopausal osteoporosis (POP). However, their ther...

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Detalles Bibliográficos
Autores principales: Zhang, Fangqing, Li, Qiuyue, Wu, Jiashuo, Ruan, Haonan, Sun, Chuanrui, Zhu, Jia, Song, Qinghui, Wei, Xu, Shi, Yue, Zhu, Liguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279576/
https://www.ncbi.nlm.nih.gov/pubmed/35846330
http://dx.doi.org/10.3389/fendo.2022.920931